Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine

Cyclolipopeptides derived from the antimicrobial peptide c(Lys-Lys-Leu-Lys-Lys-Phe-Lys-Lys-Leu-Gln) (BPC194) were prepared on solid-phase and screened against four plant pathogens. The incorporation at Lys(5) of fatty acids of 4 to 9 carbon atoms led to active cyclolipopeptides. The influence on the...

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Detalles Bibliográficos
Autores principales: Vilà, Sílvia, Badosa, Esther, Montesinos, Emilio, Planas, Marta, Feliu, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805166/
https://www.ncbi.nlm.nih.gov/pubmed/27008420
http://dx.doi.org/10.1371/journal.pone.0151639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805166/
https://www.ncbi.nlm.nih.gov/pubmed/27008420
http://dx.doi.org/10.1371/journal.pone.0151639

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