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ALFY-Controlled DVL3 Autophagy Regulates Wnt Signaling, Determining Human Brain Size
Primary microcephaly is a congenital neurodevelopmental disorder of reduced head circumference and brain volume, with fewer neurons in the cortex of the developing brain due to premature transition between symmetrical and asymmetrical cellular division of the neuronal stem cell layer during neurogen...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805177/ https://www.ncbi.nlm.nih.gov/pubmed/27008544 http://dx.doi.org/10.1371/journal.pgen.1005919 |