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Maternal Antibody-Mediated Disease Enhancement in Type I Interferon-Deficient Mice Leads to Lethal Disease Associated with Liver Damage

Epidemiological studies have reported that most of the severe dengue cases occur upon a secondary heterologous infection. Furthermore, babies born to dengue immune mothers are at greater risk of developing severe disease upon primary infection with a heterologous or homologous dengue virus (DENV) se...

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Detalles Bibliográficos
Autores principales: Martínez Gómez, Julia María, Ong, Li Ching, Lam, Jian Hang, Binte Aman, Siti Amanlina, Libau, Eshele Anak, Lee, Pei Xuan, St. John, Ashley L., Alonso, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805191/
https://www.ncbi.nlm.nih.gov/pubmed/27007501
http://dx.doi.org/10.1371/journal.pntd.0004536