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RBP2 Promotes Adult Acute Lymphoblastic Leukemia by Upregulating BCL2

Despite recent increases in the cure rate of acute lymphoblastic leukemia (ALL), adult ALL remains a high-risk disease that exhibits a high relapse rate. In this study, we found that the histone demethylase retinoblastoma binding protein-2 (RBP2) was overexpressed in both on-going and relapse cases...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoming, Zhou, Minran, Fu, Yue, Sun, Ting, Chen, Jin, Qin, Xuemei, Yu, Yuan, Jia, Jihui, Chen, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805198/
https://www.ncbi.nlm.nih.gov/pubmed/27008505
http://dx.doi.org/10.1371/journal.pone.0152142