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A Rapid and Improved Method to Generate Recombinant Dengue Virus Vaccine Candidates

Dengue is one of the most important mosquito-borne infections accounting for severe morbidity and mortality worldwide. Recently, the tetravalent chimeric live attenuated Dengue vaccine Dengvaxia(®) was approved for use in several dengue endemic countries. In general, live attenuated vaccines (LAV) a...

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Detalles Bibliográficos
Autores principales: Govindarajan, Dhanasekaran, Guan, Liming, Meschino, Steven, Fridman, Arthur, Bagchi, Ansu, Pak, Irene, ter Meulen, Jan, Casimiro, Danilo R., Bett, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805244/
https://www.ncbi.nlm.nih.gov/pubmed/27008550
http://dx.doi.org/10.1371/journal.pone.0152209