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Evolutionary Conserved Positions Define Protein Conformational Diversity

Conformational diversity of the native state plays a central role in modulating protein function. The selection paradigm sustains that different ligands shift the conformational equilibrium through their binding to highest-affinity conformers. Intramolecular vibrational dynamics associated to each c...

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Detalles Bibliográficos
Autores principales:	Saldaño, Tadeo E., Monzon, Alexander M., Parisi, Gustavo, Fernandez-Alberti, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805271/ https://www.ncbi.nlm.nih.gov/pubmed/27008419 http://dx.doi.org/10.1371/journal.pcbi.1004775

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