Peptidomimetic Star Polymers for Targeting Biological Ion Channels

Four end-functionalized star polymers that could attenuate the flow of ionic currents across biological ion channels were first de novo designed computationally, then synthesized and tested experimentally on mammalian K(+) channels. The 4-arm ethylene glycol conjugate star polymers with lysine or a...

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Detalles Bibliográficos
Autores principales: Chen, Rong, Lu, Derong, Xie, Zili, Feng, Jing, Jia, Zhongfan, Ho, Junming, Coote, Michelle L., Wu, Yingliang, Monteiro, Michael J., Chung, Shin-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805292/
https://www.ncbi.nlm.nih.gov/pubmed/27007701
http://dx.doi.org/10.1371/journal.pone.0152169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805292/
https://www.ncbi.nlm.nih.gov/pubmed/27007701
http://dx.doi.org/10.1371/journal.pone.0152169

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