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Peptidomimetic Star Polymers for Targeting Biological Ion Channels
Four end-functionalized star polymers that could attenuate the flow of ionic currents across biological ion channels were first de novo designed computationally, then synthesized and tested experimentally on mammalian K(+) channels. The 4-arm ethylene glycol conjugate star polymers with lysine or a...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805292/ https://www.ncbi.nlm.nih.gov/pubmed/27007701 http://dx.doi.org/10.1371/journal.pone.0152169 |