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The -137G/C Polymorphism in Interleukin-18 Gene Promoter Contributes to Chronic Lymphocytic and Chronic Myelogenous Leukemia Risk in Turkish Patients

OBJECTIVE: Interleukin-18 (IL-18) is a cytokine that belongs to the IL-1 superfamily and is secreted by various immune and nonimmune cells. Evidence has shown that IL-18 has both anticancer and procancer effects. The aim of this study was to evaluate the relationship between IL-18 gene polymorphisms...

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Detalles Bibliográficos
Autores principales: Yalçın, Serap, Mutlu, Pelin, Çetin, Türker, Sarper, Meral, Özgür, Gökhan, Avcu, Ferit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805319/
https://www.ncbi.nlm.nih.gov/pubmed/26376814
http://dx.doi.org/10.4274/tjh.2014.0126