Cargando…
On-Demand Targeting: Investigating Biology with Proximity-Directed Chemistry
[Image: see text] Proximity enhancement is a central chemical tenet underpinning an exciting suite of small-molecule toolsets that have allowed us to unravel many biological complexities. The leitmotif of this opus is “tethering”—a strategy in which a multifunctional small molecule serves as a templ...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2016
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805449/ https://www.ncbi.nlm.nih.gov/pubmed/26907082 http://dx.doi.org/10.1021/jacs.5b12608 |