Cargando…
LRIG1 opposes epithelial to mesenchymal transition and inhibits invasion of basal-like breast cancer cells
LRIG1, a member of the LRIG family of transmembrane leucine rich repeat-containing proteins, is a negative regulator of receptor tyrosine kinase signaling and a tumor suppressor. LRIG1 expression is broadly decreased in human cancer and in breast cancer, low expression of LRIG1 has been linked to de...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805527/ https://www.ncbi.nlm.nih.gov/pubmed/26387542 http://dx.doi.org/10.1038/onc.2015.345 |