Cargando…

LRIG1 opposes epithelial to mesenchymal transition and inhibits invasion of basal-like breast cancer cells

LRIG1, a member of the LRIG family of transmembrane leucine rich repeat-containing proteins, is a negative regulator of receptor tyrosine kinase signaling and a tumor suppressor. LRIG1 expression is broadly decreased in human cancer and in breast cancer, low expression of LRIG1 has been linked to de...

Descripción completa

Detalles Bibliográficos
Autores principales: Yokdang, Nucharee, Hatakeyama, Jason, Wald, Jessica H., Simion, Catalina, Tellez, Joseph D., Chang, Dennis Z., Swamynathan, Manojit Mosur, Chen, Mingyi, Murphy, William J., Carraway, Kermit L., Sweeney, Colleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805527/
https://www.ncbi.nlm.nih.gov/pubmed/26387542
http://dx.doi.org/10.1038/onc.2015.345