Resolving rates of mutation in the brain using single-neuron genomics

Whether somatic mutations contribute functional diversity to brain cells is a long-standing question. Single-neuron genomics enables direct measurement of somatic mutation rates in human brain and promises to answer this question. A recent study (Upton et al., 2015) reported high rates of somatic LI...

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Detalles Bibliográficos
Autores principales: Evrony, Gilad D, Lee, Eunjung, Park, Peter J, Walsh, Christopher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Genomics and Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805530/
https://www.ncbi.nlm.nih.gov/pubmed/26901440
http://dx.doi.org/10.7554/eLife.12966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805530/
https://www.ncbi.nlm.nih.gov/pubmed/26901440
http://dx.doi.org/10.7554/eLife.12966

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