The RNA binding protein IMP3 facilitates tumor immune escape by downregulating the stress-induced ligands ULPB2 and MICB

Expression of the stress-induced ligands MICA, MICB and ULBP 1–6 are up-regulated as a cellular response to DNA damage, excessive proliferation or viral infection; thereby, they enable recognition and annihilation by immune cells that express the powerful activating receptor NKG2D. This receptor is...

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Detalles Bibliográficos
Autores principales: Schmiedel, Dominik, Tai, Julie, Yamin, Rachel, Berhani, Orit, Bauman, Yoav, Mandelboim, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805531/
https://www.ncbi.nlm.nih.gov/pubmed/26982091
http://dx.doi.org/10.7554/eLife.13426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805531/
https://www.ncbi.nlm.nih.gov/pubmed/26982091
http://dx.doi.org/10.7554/eLife.13426

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