Cargando…
Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction
Women live on average longer than men but have greater levels of late-life morbidity. We have uncovered a substantial sex difference in the pathology of the aging gut in Drosophila. The intestinal epithelium of the aging female undergoes major deterioration, driven by intestinal stem cell (ISC) divi...
Autores principales: | Regan, Jennifer C, Khericha, Mobina, Dobson, Adam J, Bolukbasi, Ekin, Rattanavirotkul, Nattaphong, Partridge, Linda |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805549/ https://www.ncbi.nlm.nih.gov/pubmed/26878754 http://dx.doi.org/10.7554/eLife.10956 |
Ejemplares similares
-
Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity
por: Bolukbasi, Ekin, et al.
Publicado: (2017) -
A robust transcriptional program in newts undergoing multiple events of lens regeneration throughout their lifespan
por: Sousounis, Konstantinos, et al.
Publicado: (2015) -
Short-Term, Intermittent Fasting Induces Long-Lasting Gut Health and TOR-Independent Lifespan Extension
por: Catterson, James H., et al.
Publicado: (2018) -
Mobilization of LINE-1 retrotransposons is restricted by
Tex19.1 in mouse embryonic stem cells
por: MacLennan, Marie, et al.
Publicado: (2017) -
Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells
por: Kumar, Nathan, et al.
Publicado: (2015)