The MAP kinase pathway coordinates crossover designation with disassembly of synaptonemal complex proteins during meiosis

Asymmetric disassembly of the synaptonemal complex (SC) is crucial for proper meiotic chromosome segregation. However, the signaling mechanisms that directly regulate this process are poorly understood. Here we show that the mammalian Rho GEF homolog, ECT-2, functions through the conserved RAS/ERK M...

Descripción completa

Detalles Bibliográficos
Autores principales: Nadarajan, Saravanapriah, Mohideen, Firaz, Tzur, Yonatan B, Ferrandiz, Nuria, Crawley, Oliver, Montoya, Alex, Faull, Peter, Snijders, Ambrosius P, Cutillas, Pedro R, Jambhekar, Ashwini, Blower, Michael D, Martinez-Perez, Enrique, Harper, J Wade, Colaiacovo, Monica P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805554/
https://www.ncbi.nlm.nih.gov/pubmed/26920220
http://dx.doi.org/10.7554/eLife.12039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805554/
https://www.ncbi.nlm.nih.gov/pubmed/26920220
http://dx.doi.org/10.7554/eLife.12039

Ejemplares similares