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Inhibition of DNA–Topoisomerase I by Acylated Triterpene Saponins from Pittosporum angustifolium Lodd.

ABSTRACT: Previous phytochemical investigation of the leaves and seeds of Pittosporum angustifolium Lodd. led to the isolation and structural elucidation of polyphenols and triterpene saponins. Evaluation for cytotoxicity of isolated saponins revealed that the predominant structural feature for a cy...

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Detalles Bibliográficos
Autores principales: Bäcker, Christian, Drwal, Malgorzata N., Preissner, Robert, Lindequist, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805651/
https://www.ncbi.nlm.nih.gov/pubmed/26803837
http://dx.doi.org/10.1007/s13659-016-0087-5