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Multimodal Somatostatin Receptor Theranostics Using [(64)Cu]Cu-/[(177)Lu]Lu-DOTA-(Tyr(3))octreotate and AN-238 in a Mouse Pheochromocytoma Model

Pheochromocytomas and extra-adrenal paragangliomas (PHEO/PGLs) are rare catecholamine-producing chromaffin cell tumors. For metastatic disease, no effective therapy is available. Overexpression of somatostatin type 2 receptors (SSTR2) in PHEO/PGLs promotes interest in applying therapies using somato...

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Detalles Bibliográficos
Autores principales: Ullrich, Martin, Bergmann, Ralf, Peitzsch, Mirko, Zenker, Erik F., Cartellieri, Marc, Bachmann, Michael, Ehrhart-Bornstein, Monika, Block, Norman L., Schally, Andrew V., Eisenhofer, Graeme, Bornstein, Stefan R., Pietzsch, Jens, Ziegler, Christian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805660/
https://www.ncbi.nlm.nih.gov/pubmed/27022413
http://dx.doi.org/10.7150/thno.14479