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α(V)β(3) integrin-targeted microSPECT/CT imaging of inflamed atherosclerotic plaques in mice
BACKGROUND: α(V)β(3)-integrin is expressed by activated endothelial cells and macrophages in atherosclerotic plaques and may represent a valuable marker of high-risk plaques. We evaluated (99m)Tc-maraciclatide, an integrin-specific tracer, for imaging vascular inflammation in atherosclerotic lesions...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805679/ https://www.ncbi.nlm.nih.gov/pubmed/27009066 http://dx.doi.org/10.1186/s13550-016-0184-9 |