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α(V)β(3) integrin-targeted microSPECT/CT imaging of inflamed atherosclerotic plaques in mice

BACKGROUND: α(V)β(3)-integrin is expressed by activated endothelial cells and macrophages in atherosclerotic plaques and may represent a valuable marker of high-risk plaques. We evaluated (99m)Tc-maraciclatide, an integrin-specific tracer, for imaging vascular inflammation in atherosclerotic lesions...

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Detalles Bibliográficos
Autores principales: Vancraeynest, David, Roelants, Véronique, Bouzin, Caroline, Hanin, François-Xavier, Walrand, Stephan, Bol, Vanesa, Bol, Anne, Pouleur, Anne-Catherine, Pasquet, Agnès, Gerber, Bernhard, Lesnik, Philippe, Huby, Thierry, Jamar, François, Vanoverschelde, Jean-Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805679/
https://www.ncbi.nlm.nih.gov/pubmed/27009066
http://dx.doi.org/10.1186/s13550-016-0184-9