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In vitro anthelmintic efficacy of inhibitors of phosphoethanolamine Methyltransferases in Haemonchus contortus

The essential phosphobase methylation pathway for synthesis of phosphocholine is unique to nematodes, protozoa and plants, and thus an attractive antiparasitic molecular target. Herein, we screened compounds from the National Cancer Institute (Developmental Therapeutics Program Open Chemical Reposit...

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Detalles Bibliográficos
Autores principales: Witola, William H., Matthews, Kwame, McHugh, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805780/
https://www.ncbi.nlm.nih.gov/pubmed/27054063
http://dx.doi.org/10.1016/j.ijpddr.2016.01.002