The C-Terminus of Human Copper Importer Ctr1 Acts as a Binding Site and Transfers Copper to Atox1

Uptake of copper (Cu) ions into human cells is mediated by the plasma membrane protein Ctr1 and is followed by Cu transfer to cytoplasmic Cu chaperones for delivery to Cu-dependent enzymes. The C-terminal cytoplasmic tail of Ctr1 is a 13-residue peptide harboring an HCH motif that is thought to inte...

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Detalles Bibliográficos
Autores principales: Kahra, Dana, Kovermann, Michael, Wittung-Stafshede, Pernilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2016
Materias:
Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805863/
https://www.ncbi.nlm.nih.gov/pubmed/26745413
http://dx.doi.org/10.1016/j.bpj.2015.11.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805863/
https://www.ncbi.nlm.nih.gov/pubmed/26745413
http://dx.doi.org/10.1016/j.bpj.2015.11.016

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