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The SNARE VAMP7 Regulates Exocytic Trafficking of Interleukin-12 in Dendritic Cells

Interleukin-12 (IL-12), produced by dendritic cells in response to activation, is central to pathogen eradication and tumor rejection. The trafficking pathways controlling spatial distribution and intracellular transport of IL-12 vesicles to the cell surface are still unknown. Here, we show that int...

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Detalles Bibliográficos
Autores principales: Chiaruttini, Giulia, Piperno, Giulia M., Jouve, Mabel, De Nardi, Francesca, Larghi, Paola, Peden, Andrew A., Baj, Gabriele, Müller, Sabina, Valitutti, Salvatore, Galli, Thierry, Benvenuti, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806224/
https://www.ncbi.nlm.nih.gov/pubmed/26972013
http://dx.doi.org/10.1016/j.celrep.2016.02.055