Metabolism and Metabolic Inhibition of Xanthotoxol in Human Liver Microsomes

Cytochrome p450 (CYP450) enzymes are predominantly involved in Phase I metabolism of xenobiotics. In this study, the CYP450 isoforms involved in xanthotoxol metabolism were identified using recombinant CYP450s. In addition, the inhibitory effects of xanthotoxol on eight CYP450 isoforms and its pharm...

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Detalles Bibliográficos
Autores principales: Ma, Zhongnv, Shi, Xianbao, Zhang, Gang, Guo, Feng, Shan, Lina, Cai, Jiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806279/
https://www.ncbi.nlm.nih.gov/pubmed/27034690
http://dx.doi.org/10.1155/2016/5416509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806279/
https://www.ncbi.nlm.nih.gov/pubmed/27034690
http://dx.doi.org/10.1155/2016/5416509

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