Small molecule-mediated up-regulation of microRNA targeting a key cell death modulator BNIP3 improves cardiac function following ischemic injury

Genetic ablation of BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3), an essential regulator of cardiac cell death, is an effective way to prevent cardiac cell death triggered by pathologic conditions. However, currently there exists no known means, such as inhibitors, to down-regula...

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Detalles Bibliográficos
Autores principales: Lee, Se-Yeon, Lee, Seahyoung, Choi, Eunhyun, Ham, Onju, Lee, Chang Youn, Lee, Jiyun, Seo, Hyang-Hee, Cha, Min-Ji, Mun, Bohyun, Lee, Yunmi, Yoon, Cheesoon, Hwang, Ki-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806297/
https://www.ncbi.nlm.nih.gov/pubmed/27008992
http://dx.doi.org/10.1038/srep23472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806297/
https://www.ncbi.nlm.nih.gov/pubmed/27008992
http://dx.doi.org/10.1038/srep23472

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