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Small molecule-mediated up-regulation of microRNA targeting a key cell death modulator BNIP3 improves cardiac function following ischemic injury
Genetic ablation of BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3), an essential regulator of cardiac cell death, is an effective way to prevent cardiac cell death triggered by pathologic conditions. However, currently there exists no known means, such as inhibitors, to down-regula...
Autores principales: | Lee, Se-Yeon, Lee, Seahyoung, Choi, Eunhyun, Ham, Onju, Lee, Chang Youn, Lee, Jiyun, Seo, Hyang-Hee, Cha, Min-Ji, Mun, Bohyun, Lee, Yunmi, Yoon, Cheesoon, Hwang, Ki-Chul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806297/ https://www.ncbi.nlm.nih.gov/pubmed/27008992 http://dx.doi.org/10.1038/srep23472 |
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