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Dynamin II is required for 17β-estradiol signaling and autophagy-based ERα degradation

17β-estradiol (E2) regulates diverse physiological effects, including cell proliferation, by binding to estrogen receptor α (ERα). ERα is both a transcription factor that drives E2-sensitive gene expression and an extra-nuclear localized receptor that triggers the activation of diverse kinase cascad...

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Detalles Bibliográficos
Autores principales: Totta, Pierangela, Busonero, Claudia, Leone, Stefano, Marino, Maria, Acconcia, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806323/
https://www.ncbi.nlm.nih.gov/pubmed/27009360
http://dx.doi.org/10.1038/srep23727