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The fetal thymus has a unique genomic copy number profile resulting from physiological T cell receptor gene rearrangement

Somatic mosaicism, the presence of genetically distinct cells within an organism, has been increasingly associated with human morbidity, ranging from being a cause of rare syndromes to a risk factor for common disorders such as malignancy and cardiovascular disease. Previous studies interrogating th...

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Detalles Bibliográficos
Autores principales: Valind, Anders, Haikal, C., Klasson, M. E. K., Johansson, M. C., Gullander, J., Soller, M., Baldetorp, B., Gisselsson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806331/
https://www.ncbi.nlm.nih.gov/pubmed/27009469
http://dx.doi.org/10.1038/srep23500