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Paclitaxel-loaded phosphonated calixarene nanovesicles as a modular drug delivery platform

A modular p-phosphonated calix[4]arene vesicle (PCV) loaded with paclitaxel (PTX) and conjugated with folic acid as a cancer targeting ligand has been prepared using a thin film-sonication method. It has a pH-responsive capacity to trigger the release of the encapsulated PTX payload under mildly aci...

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Detalles Bibliográficos
Autores principales: Mo, Jingxin, Eggers, Paul K., Yuan, Zhi-xiang, Raston, Colin L., Lim, Lee Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806332/
https://www.ncbi.nlm.nih.gov/pubmed/27009430
http://dx.doi.org/10.1038/srep23489