WIP and WICH/WIRE co-ordinately control invadopodium formation and maturation in human breast cancer cell invasion

Cancer cells form actin-rich degradative protrusions (invasive pseudopods and invadopodia), which allows their efficient dispersal during metastasis. Using biochemical and advanced imaging approaches, we demonstrate that the N-WASP-interactors WIP and WICH/WIRE play non-redundant roles in cancer cel...

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Detalles Bibliográficos
Autores principales: García, Esther, Ragazzini, Chiara, Yu, Xinzi, Cuesta-García, Elena, Bernardino de la Serna, Jorge, Zech, Tobias, Sarrió, David, Machesky, Laura M., Antón, Inés M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806363/
https://www.ncbi.nlm.nih.gov/pubmed/27009365
http://dx.doi.org/10.1038/srep23590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806363/
https://www.ncbi.nlm.nih.gov/pubmed/27009365
http://dx.doi.org/10.1038/srep23590

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