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WIP and WICH/WIRE co-ordinately control invadopodium formation and maturation in human breast cancer cell invasion
Cancer cells form actin-rich degradative protrusions (invasive pseudopods and invadopodia), which allows their efficient dispersal during metastasis. Using biochemical and advanced imaging approaches, we demonstrate that the N-WASP-interactors WIP and WICH/WIRE play non-redundant roles in cancer cel...
Autores principales: | García, Esther, Ragazzini, Chiara, Yu, Xinzi, Cuesta-García, Elena, Bernardino de la Serna, Jorge, Zech, Tobias, Sarrió, David, Machesky, Laura M., Antón, Inés M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806363/ https://www.ncbi.nlm.nih.gov/pubmed/27009365 http://dx.doi.org/10.1038/srep23590 |
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