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HBx-upregulated lncRNA UCA1 promotes cell growth and tumorigenesis by recruiting EZH2 and repressing p27Kip1/CDK2 signaling

It is well accepted that HBx plays the major role in hepatocarcinogenesis associated with hepatitis B virus (HBV) infections. However, little was known about its role in regulating long noncoding RNAs (lncRNAs), a large group of transcripts regulating a variety of biological processes including carc...

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Detalles Bibliográficos
Autores principales: Hu, Jiao-Jiao, Song, Wei, Zhang, Shao-Dan, Shen, Xiao-Hui, Qiu, Xue-Mei, Wu, Hua-Zhang, Gong, Pi-Hai, Lu, Sen, Zhao, Zhu-Jiang, He, Ming-Liang, Fan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806364/
https://www.ncbi.nlm.nih.gov/pubmed/27009634
http://dx.doi.org/10.1038/srep23521