Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment

Caspase-2 plays an important role in apoptosis induced by several stimuli, including oxidative stress. However, the subcellular localization of caspase-2, particularly its presence in the mitochondria, is unclear. It is also not known if cytosolic caspase-2 translocates to the mitochondria to trigge...

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Detalles Bibliográficos
Autores principales: Lopez-Cruzan, M, Sharma, R, Tiwari, M, Karbach, S, Holstein, D, Martin, C R, Lechleiter, J D, Herman, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806400/
https://www.ncbi.nlm.nih.gov/pubmed/27019748
http://dx.doi.org/10.1038/cddiscovery.2016.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806400/
https://www.ncbi.nlm.nih.gov/pubmed/27019748
http://dx.doi.org/10.1038/cddiscovery.2016.5

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