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Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment
Caspase-2 plays an important role in apoptosis induced by several stimuli, including oxidative stress. However, the subcellular localization of caspase-2, particularly its presence in the mitochondria, is unclear. It is also not known if cytosolic caspase-2 translocates to the mitochondria to trigge...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806400/ https://www.ncbi.nlm.nih.gov/pubmed/27019748 http://dx.doi.org/10.1038/cddiscovery.2016.5 |