CCR7 mediates the TNF-α-induced lymphatic metastasis of gallbladder cancer through the “ERK1/2 - AP-1” and “JNK - AP-1” pathways

BACKGROUND: CC-chemokine receptor 7 (CCR7), which plays an important role in cell directional movement, is highly expressed in various cancers and positively related to lymph node metastasis. The inflammatory cytokine tumour necrosis factor (TNF)-α promotes tumour progression and lymph node metastas...

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Detalles Bibliográficos
Autores principales: Hong, HaiJie, He, CaiLong, Zhu, SiYuan, Zhang, YanHui, Wang, XiaoQian, She, FeiFei, Chen, YanLing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806413/
https://www.ncbi.nlm.nih.gov/pubmed/27009073
http://dx.doi.org/10.1186/s13046-016-0318-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806413/
https://www.ncbi.nlm.nih.gov/pubmed/27009073
http://dx.doi.org/10.1186/s13046-016-0318-y

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