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Complex molecular and functional outcomes of single versus sequential cytokine stimulation of rat microglia

BACKGROUND: Microglia are the “professional” phagocytes of the CNS. Phagocytosis is crucial for normal CNS development and maintenance, but it can be either beneficial or detrimental after injury or disease. For instance, white matter damage releases myelin debris that must be cleared by microglia i...

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Detalles Bibliográficos
Autores principales: Siddiqui, Tamjeed A., Lively, Starlee, Schlichter, Lyanne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806433/
https://www.ncbi.nlm.nih.gov/pubmed/27009332
http://dx.doi.org/10.1186/s12974-016-0531-9