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Efficient identification of CRISPR/Cas9-induced insertions/deletions by direct germline screening in zebrafish
BACKGROUND: The CRISPR/Cas9 system is a prokaryotic immune system that infers resistance to foreign genetic material and is a sort of 'adaptive immunity'. It has been adapted to enable high throughput genome editing and has revolutionised the generation of targeted mutations. RESULTS: We h...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806435/ https://www.ncbi.nlm.nih.gov/pubmed/27009152 http://dx.doi.org/10.1186/s12864-016-2563-z |