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Differential responsiveness of Holstein and Angus dermal fibroblasts to LPS challenge occurs without major differences in the methylome

BACKGROUND: We have previously found substantial animal-to-animal and age-dependent variation in the response of Holstein fibroblast cultures challenged with LPS. To expand on this finding, fibroblast cultures were established from dairy (Holstein) and beef (Angus) cattle and challenged with LPS to...

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Detalles Bibliográficos
Autores principales: Benjamin, Aimee L., Green, Benjamin B., Crooker, Brian A., McKay, Stephanie D., Kerr, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806443/
https://www.ncbi.nlm.nih.gov/pubmed/27009155
http://dx.doi.org/10.1186/s12864-016-2565-x