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Dynamics of BMP and Hes1/Hairy1 signaling in the dorsal neural tube underlies the transition from neural crest to definitive roof plate

BACKGROUND: The dorsal midline region of the neural tube that results from closure of the neural folds is generally termed the roof plate (RP). However, this domain is highly dynamic and complex, and is first transiently inhabited by prospective neural crest (NC) cells that sequentially emigrate fro...

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Detalles Bibliográficos
Autores principales: Nitzan, Erez, Avraham, Oshri, Kahane, Nitza, Ofek, Shai, Kumar, Deepak, Kalcheim, Chaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806459/
https://www.ncbi.nlm.nih.gov/pubmed/27012662
http://dx.doi.org/10.1186/s12915-016-0245-6