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Blinding in randomized controlled trials in general and abdominal surgery: protocol for a systematic review and empirical study

BACKGROUND: Blinding is a measure in randomized controlled trials (RCT) to reduce detection and performance bias. There is evidence that lack of blinding leads to overestimated treatment effects. Because of the physical component of interventions, blinding is not easily applicable in surgical trials...

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Detalles Bibliográficos
Autores principales: Probst, Pascal, Grummich, Kathrin, Heger, Patrick, Zaschke, Steffen, Knebel, Phillip, Ulrich, Alexis, Büchler, Markus W., Diener, Markus K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806514/
https://www.ncbi.nlm.nih.gov/pubmed/27012940
http://dx.doi.org/10.1186/s13643-016-0226-4