Inhibition of hepatitis C virus RNA replication by ISG15 does not require its conjugation to protein substrates by the HERC5 E3 ligase

Chronic infection of the liver by hepatitis C virus (HCV) induces a range of host factors including IFN-stimulated genes such as ISG15. ISG15 functions as an antiviral factor that limits virus replication. Previous studies have suggested that ISG15 could influence HCV replication in both a positive...

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Detalles Bibliográficos
Autores principales: Domingues, Patricia, Bamford, Connor G. G., Boutell, Chris, McLauchlan, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806579/
https://www.ncbi.nlm.nih.gov/pubmed/26361997
http://dx.doi.org/10.1099/jgv.0.000283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806579/
https://www.ncbi.nlm.nih.gov/pubmed/26361997
http://dx.doi.org/10.1099/jgv.0.000283

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