Development of Immunocapture-LC/MS Assay for Simultaneous ADA Isotyping and Semiquantitation

Therapeutic proteins and peptides have potential to elicit immune responses resulting in anti-drug antibodies that can pose problems for both patient safety and product efficacy. During drug development immunogenicity is usually examined by risk-based approach along with specific strategies for deve...

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Detalles Bibliográficos
Autores principales: Chen, Lin-Zhi, Roos, David, Philip, Elsy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806687/
https://www.ncbi.nlm.nih.gov/pubmed/27034966
http://dx.doi.org/10.1155/2016/7682472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806687/
https://www.ncbi.nlm.nih.gov/pubmed/27034966
http://dx.doi.org/10.1155/2016/7682472

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