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Development of Immunocapture-LC/MS Assay for Simultaneous ADA Isotyping and Semiquantitation
Therapeutic proteins and peptides have potential to elicit immune responses resulting in anti-drug antibodies that can pose problems for both patient safety and product efficacy. During drug development immunogenicity is usually examined by risk-based approach along with specific strategies for deve...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806687/ https://www.ncbi.nlm.nih.gov/pubmed/27034966 http://dx.doi.org/10.1155/2016/7682472 |