Aberrant expression of microRNA-99a and its target gene mTOR associated with malignant progression and poor prognosis in patients with osteosarcoma

BACKGROUND: The mammalian target of rapamycin (mTOR) has been reported to act as a target gene of microRNA (miR)-99a in various cancer cells and identified as an independent prognostic marker of human osteosarcoma. The aim of this study was to investigate the clinical significance of miR-99a/mTOR ax...

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Detalles Bibliográficos
Autores principales: Zhao, Jiali, Chen, Fengli, Zhou, Quan, Pan, Wei, Wang, Xinhong, Xu, Jin, Ni, Li, Yang, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806763/
https://www.ncbi.nlm.nih.gov/pubmed/27073323
http://dx.doi.org/10.2147/OTT.S102421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806763/
https://www.ncbi.nlm.nih.gov/pubmed/27073323
http://dx.doi.org/10.2147/OTT.S102421

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