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YAP induces cisplatin resistance through activation of autophagy in human ovarian carcinoma cells
OBJECTIVE: To identify the role of YAP in cisplatin resistance in human ovarian cancer cells and in the regulation of autophagy in these cancer cells. MATERIALS AND METHODS: The cisplatin-sensitive OV2008 parental cell line and its cisplatin-resistant variant C13K were cultured. RNA interference was...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806764/ https://www.ncbi.nlm.nih.gov/pubmed/27073322 http://dx.doi.org/10.2147/OTT.S102837 |