Structural and Functional Analysis of Calcium Ion Mediated Binding of 5-Lipoxygenase to Nanodiscs

An important step in the production of inflammatory mediators of the leukotriene family is the Ca(2+) mediated recruitment of 5 Lipoxygenase (5LO) to nuclear membranes. To study this reaction in vitro, the natural membrane mimicking environment of nanodiscs was used. Nanodiscs with 10.5 nm inner dia...

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Detalles Bibliográficos
Autores principales: Kumar, Ramakrishnan B., Zhu, Lin, Idborg, Helena, Rådmark, Olof, Jakobsson, Per-Johan, Rinaldo-Matthis, Agnes, Hebert, Hans, Jegerschöld, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806843/
https://www.ncbi.nlm.nih.gov/pubmed/27010627
http://dx.doi.org/10.1371/journal.pone.0152116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806843/
https://www.ncbi.nlm.nih.gov/pubmed/27010627
http://dx.doi.org/10.1371/journal.pone.0152116

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