A Bayesian Assignment Method for Ambiguous Bisulfite Short Reads

DNA methylation is an epigenetic modification critical for normal development and diseases. The determination of genome-wide DNA methylation at single-nucleotide resolution is made possible by sequencing bisulfite treated DNA with next generation high-throughput sequencing. However, aligning bisulfi...

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Detalles Bibliográficos
Autores principales: Tran, Hong, Wu, Xiaowei, Tithi, Saima, Sun, Ming-an, Xie, Hehuang, Zhang, Liqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806927/
https://www.ncbi.nlm.nih.gov/pubmed/27011215
http://dx.doi.org/10.1371/journal.pone.0151826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806927/
https://www.ncbi.nlm.nih.gov/pubmed/27011215
http://dx.doi.org/10.1371/journal.pone.0151826

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