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Genome-Wide Analysis in Swine Associates Corneal Graft Rejection with Donor-Recipient Mismatches in Three Novel Histocompatibility Regions and One Locus Homologous to the Mouse H-3 Locus

In rodents, immune responses to minor histocompatibility antigens are the most important drivers of corneal graft rejection. However, this has not been confirmed in humans or in a large animal model and the genetic loci are poorly characterised, even in mice. The gene sequence data now available for...

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Detalles Bibliográficos
Autores principales: Nicholls, Susan, Pong-Wong, Ricardo, Mitchard, Louisa, Harley, Ross, Archibald, Alan, Dick, Andrew, Bailey, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806994/
https://www.ncbi.nlm.nih.gov/pubmed/27010211
http://dx.doi.org/10.1371/journal.pone.0152155