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Genome-Wide Analysis in Swine Associates Corneal Graft Rejection with Donor-Recipient Mismatches in Three Novel Histocompatibility Regions and One Locus Homologous to the Mouse H-3 Locus
In rodents, immune responses to minor histocompatibility antigens are the most important drivers of corneal graft rejection. However, this has not been confirmed in humans or in a large animal model and the genetic loci are poorly characterised, even in mice. The gene sequence data now available for...
Autores principales: | Nicholls, Susan, Pong-Wong, Ricardo, Mitchard, Louisa, Harley, Ross, Archibald, Alan, Dick, Andrew, Bailey, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806994/ https://www.ncbi.nlm.nih.gov/pubmed/27010211 http://dx.doi.org/10.1371/journal.pone.0152155 |
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