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UmuDAb: An Error-Prone Polymerase Accessory Homolog Whose N-Terminal Domain Is Required for Repression of DNA Damage Inducible Gene Expression in Acinetobacter baylyi

In many bacteria, the DNA damage response induces genes (SOS genes) that were repressed by LexA. LexA represses transcription by binding to SOS promoters via a helix-turn-helix motif in its N-terminal domain (NTD). Upon DNA damage, LexA cleaves itself and allows induction of transcription. In Acinet...

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Detalles Bibliográficos
Autores principales: Witkowski, Travis A., Grice, Alison N., Stinnett, DeAnna B., Wells, Whitney K., Peterson, Megan A., Hare, Janelle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807011/
https://www.ncbi.nlm.nih.gov/pubmed/27010837
http://dx.doi.org/10.1371/journal.pone.0152013