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A Computational Model of Inhibition of HIV-1 by Interferon-Alpha

Type 1 interferons such as interferon-alpha (IFNα) inhibit replication of Human immunodeficiency virus (HIV-1) by upregulating the expression of genes that interfere with specific steps in the viral life cycle. This pathway thus represents a potential target for immune-based therapies that can alter...

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Detalles Bibliográficos
Autores principales: Browne, Edward P., Letham, Benjamin, Rudin, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807028/
https://www.ncbi.nlm.nih.gov/pubmed/27010978
http://dx.doi.org/10.1371/journal.pone.0152316